Differentiation of true anophthalmia from clinical anophthalmia using neuroradiological imaging

Anophthalmia and microphthalmia

Anophthalmia and microphthalmia describe, respectively, the absence of an eye and the presence of a small eye within the orbit. The combined birth prevalence of these conditions is up to 30 per 100,000 population, with microphthalmia reported in up to 11% of blind children. High-resolution cranial imaging, post-mortem examination and genetic studies suggest that these conditions represent a phe...

The fate of the oculomotor system in clinical bilateral anophthalmia.

The interdependence of the development of the eye and oculomotor system during embryogenesis is currently unclear. The occurrence of clinical anophthalmia, where the globe fails to develop, permits us to study the effects this has on the development of the complex neuromuscular system controlling eye movements. In this study, we use very high-resolution T2-weighted imaging in five anophthalmic ...

Expansion of the socket and orbit for congenital clinical anophthalmia.

BACKGROUND Congenital clinical anophthalmia requires fitting an artificial eye, achieving a pleasing aspect of the palpebral apparatus, and stimulating growth of the orbit, as well as of the entire midface. METHODS Out of 25 patients with clinical anophthalmia, 22 were treated according to a new protocol (first described by Wiese et al. in 1999) and followed for up to 6 years. In 10 patients,...

گزارش یک مورد آنوفتالمی(Anophthalmia)

مقدمه: آنوفتالمی و میکروفتالمی به‌صورت نبودن یک چشم یا وجود یک چشم کوچک در اربیت تعریف می‌شود که در بیش از 50درصد موارد با آنومالی‌های سیستمی همراه است و علل متعدد محیطی و کروموزومی دارد. امکان تشخیص پیش از زایمان با روش‌های تصویربرداری مثل سونوگرافی و نیز ارزیابی سیتوژن مایع آمنیون امکان‌پذیر است و درمان ایده‌ال باید هرچه زودتر بعد از زایمان آغاز شود. به‌علت نادر بودن این بیماری یعنی 30-1 در ه...

A Case of Congenital Bilateral Anophthalmia