Differentiating lower motor neuron syndromes
نویسندگان
چکیده
منابع مشابه
Differentiating lower motor neuron syndromes
Lower motor neuron (LMN) syndromes typically present with muscle wasting and weakness and may arise from pathology affecting the distal motor nerve up to the level of the anterior horn cell. A variety of hereditary causes are recognised, including spinal muscular atrophy, distal hereditary motor neuropathy and LMN variants of familial motor neuron disease. Recent genetic advances have resulted ...
متن کاملUse of human intravenous immunoglobulin in lower motor neuron syndromes.
OBJECTIVE To determine whether patients with the clinical phenotype of multifocal motor neuropathy but without the electrophysiological criteria for conduction block would respond to intravenous immunoglobulin (IVIg). METHODS Ten patients were selected with a slowly progressive, asymmetric, lower motor neuron disorder, and were treated prospectively with IVIg at a dose of 2g/kg over 5 days. A...
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Motor neuron disease is still one of the most dramatic neurological conditions; it reflects a range of which one end encompasses patients with the bulbar form of amyotrophic lateral sclerosis who have dysarthria and dysphagia and have a dramatically shortened life expectancy. For patients with probable or definite motor neuron disease according to established criteria, the recent introduction o...
متن کاملDiffuse Lower Motor Neuron Disorders
One of the causes of acute quadriparesis or quadriplegia is that of diffuse lower motor neuronal (LMN) dysfunction, resulting in diminished to absent reflexes in all 4 legs. In this instance the immediate differential diagnosis must include acute polyradiculoneuropathy (previously discussed), Coral snake envenomation, tick paralysis, and botulism. Other causes which normally result in normal re...
متن کاملPredicting a Positive Response to Intravenous Immunoglobulin in Isolated Lower Motor Neuron Syndromes
OBJECTIVE To determine clinically related characteristics in patients with pure lower motor neuron (LMN) syndromes, not fulfilling accepted diagnostic criteria, who were likely to respond to intravenous immunoglobulin (IVIg) treatment. METHODS Demographic, clinical, laboratory and neurophysiological characteristics were prospectively collected from patients with undifferentiated isolated LMN ...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2016
ISSN: 0022-3050,1468-330X
DOI: 10.1136/jnnp-2016-313526