Differential Lyn-dependence of the SHIP1-deficient mast cell phenotype

Temperature Dependence of Mast Cell Histamine Secretion

A diverse set of direct experimental observations and theoretical considerations supports the existence of fluidity in cell membranes (1) . Several membrane-dependent functions of Escherichia coli have been shown to exhibit biphasic Arrhenius plots with transition temperatures that are determined by the degree and configuration of the unsaturation of fatty acids incorporated into the membrane p...

Activation Phenotype Stem Cell Factor Programs the Mast Cell Gilfillan

Mast cells, activated by Ag via Fc«RI, release an array of proinflammatory mediators that contribute to allergic disorders, such as asthma and anaphylaxis. The KIT ligand, stem cell factor (SCF), is critical for mast cell expansion, differentiation, and survival, and under acute conditions, it enhances mast cell activation. However, extended SCF exposure in vivo conversely protects against fata...

Activation Phenotype Stem Cell Factor Programs the Mast Cell

Stem cell factor programs the mast cell activation phenotype.

Mast cells, activated by Ag via FcεRI, release an array of proinflammatory mediators that contribute to allergic disorders, such as asthma and anaphylaxis. The KIT ligand, stem cell factor (SCF), is critical for mast cell expansion, differentiation, and survival, and under acute conditions, it enhances mast cell activation. However, extended SCF exposure in vivo conversely protects against fata...

Allergic Inflammation In Vivo Hyperplasia, Cytokine Production, and SHIP1 Is a Repressor of Mast Cell