DIFFERENTIAL EFFECTS OF MYONEURAL BLOCKING DRUGS ON NEUROMUSCULAR TRANSMISSION
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چکیده
منابع مشابه
Differential effects of myoneural blocking drugs on neuromuscular transmission in infants.
Equipotent, paralysing doses of pancuronium and tubocurarine were administered to 40 patients, aged from 1 day to 12 months, during nitrous oxide, oxygen and fentanyl anaesthesia. Neuromuscular activity was measured during onset and recovery from paralysis using train-of-four stimulation. At the same depression of the first stimulus of the train, the train-of-four ratio was decreased more durin...
متن کاملThe undesirable effects of neuromuscular blocking drugs.
Neuromuscular blocking drugs are designed to bind to the nicotinic receptor at the neuromuscular junction. However, they also interact with other acetylcholine receptors in the body. Binding to these receptors causes adverse effects that vary with the specificity for the cholinergic receptor in question. Moreover, all neuromuscular blocking drugs may cause hypersensitivity reactions. Often the ...
متن کاملAdverse effects of neuromuscular blocking drugs.
Neuromuscular blocking drugs are not as notorious for producing adverse reactions as the i.v. induction agents; nevertheless, to a varying degree they all produce unfavourable or harmful effects. The newer non-depolarizing neuromuscular blockers, atracurium and vecuronium, have been developed in an attempt to overcome the disadvantages of the earlier drugs, but although much more specific agent...
متن کاملEffects of propranolol on the action of neuromuscular blocking drugs.
The use of propranolol in the treatment of arrhythmias during anaesthesia has recently been discussed by Vickers (1966). After intra-arterial injection of comparatively large doses, propranolol, like the structurally related pronethalol (Tiirker and Kiran, 1965), augments the action of neuromuscular blocking agents (Wislicki and Rosenblum, 1967). It has been shown that propranolol not only bloc...
متن کاملAnaphylaxis to neuromuscular-blocking drugs: all neuromuscular-blocking drugs are not the same.
5 January 2015 I n the current issue of Anesthesiology, Reddy et al.1 report a two-hospital, retrospective, observational, cohort study confirming that anaphylaxis is more common with rocuronium and succinylcholine than with atracurium, a topic that is difficult to assess and was first highlighted in this journal in 2003.2 Although any medication can potentially cause perioperative anaphylaxis,...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1980
ISSN: 0007-0912
DOI: 10.1093/bja/52.11.1111