Differences in clinical features of hypertrophic cardiomyopathy with or without left ventricular enlargement

Background Few studies have focused on the clinical features of hypertrophic cardiomyopathy (HCM) with enlarged left ventricle (ELV). Methods In this study, participants were patients HCM (n=170), who divided into two groups [ELV and normal (NLV)] according to size. Age at diagnosis, sex, complications, electrocardiogram (ECG), symptoms, drug treatment, echocardiographic parameters compared between NLV (n=153) ELV (n=17) groups. Results The incidence end-stage (ES-HCM) among all was 5.29%, while that 10.0%. For those asymmetric septal (ASHCM), there more males than NLV. Of ASHCM, ventricular ejection fraction (LVEF) significantly lower in group group; accordingly, rates diuretics use higher group. Among apical (ApHCM) patients, atrial diameter (LAd), fibrillation (Af) or ST-T change, rate angiotensin converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) Conclusions These findings suggest prevalence ES-HCM Additionally, is common men women are differences different types ELV.