منابع مشابه
Diethyl indolizine-1,3-dicarboxylate
The title compound, C(14)H(15)NO(4), was prepared by a 1,3-dipolar cyclo-addition from N-(eth-oxy-carbonyl-methy)pyridinium bromide and ethyl acrylate. The -CO(2) side chains form dihedral angles of 0.2 (3) and 2.4 (3)° with respect to the ring system. In the crystal, two neighbouring mol-ecules form a dimer through weak C-H⋯O interactions. The dimers form a three-dimensional structure via furt...
متن کاملDiethyl 2-amino-5-[(E)-(1-methyl-1H-pyrrol-2-yl)methylideneamino]thiophene-3,4-dicarboxylate
The structure of the title compound, C(16)H(19)N(3)O(4)S, shows the planes described by the thio-phene and the pyrroles are twisted by 17.06 (4)°. Additionally, the structure shows the azomethine bond adopts the E configuration, while the pyrrole is disordered as a heterocycle flip [occupancy ratio 0.729 (5):0.271 (5)]. The three-dimensional network is well packed and involves N-H⋯O hydrogen bo...
متن کاملDiethyl 1,4-dioxo-1,2,2a,3,4,10b-hexahydro-5H,10H-2,3,4a,10a-tetraazabenzo[g]cyclopenta[cd]azulene-2a,10b-dicarboxylate
In the title compound, C(18)H(20)N(4)O(6), the dihedral angle between the two fused five-membered rings in the glycoluril unit is 64.42 (2)°. The crystal structure features inter-molecular N-H⋯O and C-H⋯O interactions. An intramolecular C-H⋯O contact is also present.
متن کامل[Experimental study of the anti-inflammatory and analgesic effects of diethyl 1,3-dicyclohexyl- 1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylate].
OBJECTIVE To study the anti-inflammatory and analgesic activities of diethyl 1,3-dicyclohexyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylate (ZL-5010) in vivo and in vitro. METHODS The analgesic effect of ZL-5010 was evaluated by acetic acid-induced writhing response in mice, and the anti-inflammatory effects was assessed in mice with xylene-induced ear edema and in rats with carrageenan-indu...
متن کاملSydnone C-4 heteroarylation with an indolizine ring via Chichibabin indolizine synthesis
The synthesis of sydnones heteroarylated at C-4 with an indolizine was achieved by Chichibabin (Tschitschibabin) indolizine synthesis starting from the corresponding sydnone-N-pyridinium bromides. The latter compounds were also transformed to sydnone-indolizines connected through a keto group at the C-4 position by refluxing them in 1,2-epoxybutane with an activated alkyne. The structures of th...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2010
ISSN: 1600-5368
DOI: 10.1107/s1600536810050919