Dietary restriction in cerebral bioenergetics and redox state
نویسندگان
چکیده
منابع مشابه
Dietary restriction in cerebral bioenergetics and redox state☆
The brain has a central role in the regulation of energy stability of the organism. It is the organ with the highest energetic demands, the most susceptible to energy deficits, and is responsible for coordinating behavioral and physiological responses related to food foraging and intake. Dietary interventions have been shown to be a very effective means to extend lifespan and delay the appearan...
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Intermittent fasting (IF) is a dietary intervention often used as an alternative to caloric restriction (CR) and characterized by 24 hour cycles alternating ad libitum feeding and fasting. Although the consequences of CR are well studied, the effects of IF on redox status are not. Here, we address the effects of IF on redox state markers in different tissues in order to uncover how changes in f...
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1Department of Biology, University of Rome “Tor Vergata”, Via della Ricerca Scientifica, 00133 Rome, Italy 2Research Centre IRCCS San Raffaele Pisana, Via di Val Cannuta 247, 00166 Rome, Italy 3Department of Biochemistry and Molecular Biology, Institute of Functional Biology and Genomics (IBFG), IBSAL, CSIC, University of Salamanca, Calle Zacarias Gonzalez 2, 37007 Salamanca, Spain 4Department ...
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Caloric restriction (CR) has been shown to either decrease or prevent the progression of several age-related pathologies. In previous work, we demonstrated that CR modulates astrocyte functions, suggesting that CR may exert neuroglial modulation. Here, we investigated the effects of CR on hippocampal (Hc) and cortical (Cx) oxidative stress parameters of male Wistar rats. Our results showed that...
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Cells and tissues must maintain a reducing environment to survive. This reducing environment provides the electrochemical gradient needed for electron flow. This movement of electrons provides the energy needed to build and maintain cellular structures and associated functions. An array of redox couples is responsible for the electron transfer. Some of these redox couples are linked to each oth...
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ژورنال
عنوان ژورنال: Redox Biology
سال: 2014
ISSN: 2213-2317
DOI: 10.1016/j.redox.2013.12.021