منابع مشابه
Dietary restriction with and without caloric restriction for healthy aging
Caloric restriction is the most effective and reproducible dietary intervention known to regulate aging and increase the healthy lifespan in various model organisms, ranging from the unicellular yeast to worms, flies, rodents, and primates. However, caloric restriction, which in most cases entails a 20-40% reduction of food consumption relative to normal intake, is a severe intervention that re...
متن کاملAntiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors.
PURPOSE The antiangiogenic and proapoptotic mechanisms of dietary caloric restriction (DR) are unknown. In this study, we evaluated the effects of moderate (40%) DR on the orthotopic growth of mouse and human brain tumors that differ in cell origin, angiogenicity, host environment, and biochemical composition. EXPERIMENTAL DESIGN A malignant mouse astrocytoma (CT-2A) and a human glioma (U87-M...
متن کاملDietary Restriction on Hepatic Metabolism and Hepatotoxicity
Received May 8, 2007; revision accepted for publication June 18, 2007. Correspondence: Pei-Yu Wang, Department of Social Medicine and Health Education, School of Public Health, Peking University, Xueyuan Road 38, Haidian District, Beijing, 100083, China. e-mail: [email protected] One-Day Dietary Restriction Changes Hepatic Metabolism and Potentiates the Hepatotoxicity of Carbon Tetrac...
متن کاملDietary restriction and fasting downregulate complement activity
Background Seventy-two hours of preoperative fasting (F) or 2 weeks of 30% dietary restriction (DR) offers robust protection against renal ischemia-reperfusion injury (IRI) in mice. However, the mechanism remains to be elucidated. We hypothesize that immunomodulation plays a pivotal role. Innate immunity, especially the complement system, is crucial in the pathophysiology of IRI. Therefore, we ...
متن کاملSuppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms.
Dietary restriction (reduced calorie intake with nutritional maintenance) can extend lifespan and may increase the resistance of the nervous system to age-related diseases including neurodegenerative disorders. An environment enriched in intellectual and physical activities can also allay many of the adverse effects of aging on the brain. The mechanisms underlying the beneficial effects of diet...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuroscience Bulletin
سال: 2010
ISSN: 1673-7067,1995-8218
DOI: 10.1007/s12264-010-0716-7