Dietary Exposure to Aflatoxins in Some Randomly Selected Foods and Cancer Risk Estimations of Cereals Consumed on a Ghanaian Market

Aflatoxins have gained so much reputation among all mycotoxins due to their notoriety in causing countless adverse health effects on humans as well animals. It continues be a major concern food safety globally. In this study, total and constitutive aflatoxins levels the carcinogenic risks posed by 110 feed samples (55 cereals, 20 nuts oils, 18 animal feed, fruits vegetables) collected from Ho Central market Volta region, Ghana, were assessed. Using high-performance liquid chromatography connected fluorescent detector (HPLC-FLD), of (AFtotal) constituents, namely, AFB1, AFB2, AFG1, AFG2, analyzed. By using model prescribed Joint FAO/WHO Expert Committee Food Additives (JECFA), determined. The degrees toxicity ranges 0.78–234.73 μg/kg, 0.47–21.6 1.01–13.75 0.66–5.51 respectively, for AFG2. Out analyzed AFtotal, about 51 (46.4%) exceeded limits GSA range 10.63 ± 1.20–236.28 4.2 μg/kg. While EFSA, 71 (64.54%) ranged between 4.72 0.28 236.28 Furthermore, estimated daily intake (EDI) 27.10–283.70 ng/kg·bw/day, margin exposure (MOE) 1.409–14.76, average potency 0–0.00396 ng aflatoxins/kg·bw/day, cancer with 0.107–1.122 cases/100,000 person/yr observed. Taken together, it could concluded that consuming cereals pose human regardless age consumer.