Diagnostic value of diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) in differentiation between normal and abnormally thickened endometrium: prospective study

Abstract Background Diffusion tensor imaging (DTI) can be beneficial to differentiate between endometrium and other uterine layers. It is believed that it used normal abnormally thickened . The purpose of this study was find out the diagnostic value DTI as an extension DWI in characterization from normal. Results This included 68 females, results 3 them were excluded (unable complete study), so final number 65 females subdivided into 2 groups; (A) control: 24 (13 premenopausal 11 asymptomatic postmenopausal), (B) pathological endometrium: 41 (11 30 postmenopausal): benign (21 patients) malignant (20 patients). collected data correlated histopathological (as gold standard) cases endometrial pathologies. mean DW-ADC values for normal, benign, patients 1.43 ± 0.13, 1.56 0.17, 0.86 0.16 respectively with significant statistical difference lesions ( P = 0.006), lesions, ˂ 0.001). DTI-FA 0.349 0.08, 0.29 0.09, 0.299 0.08 0.02), but there no regarding or ˃ 0.05). Also, a DTI-MD (1.59 0.06) (1.37 0.09), (0.71 0.25), DT-MD had higher sensitivity, specificity, accuracy than both DT-FA differentiating Conclusion (added DWI) valuable non-invasive tool increase conditions, helping early management, decrease possibility misdiagnosis.