Diagnostic value of CD56 immunohistochemistry in thyroid lesions

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Diagnostic Value of Calretinin and S100 Immunohistochemistry in Hirschsprung's Disease

Background Rectal biopsy and its histopathological study with hematoxylin and eosin (HE) is the gold standard for Hirschsprung's disease (HD) diagnosis. However, there are some limitations in the diagnosis of ganglion cells in HE approach. Recently, it was reported that the utility of Calretinin is a reliable ancillary immunohistochemistry (IHC) test for HD diagn...

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absent cd56 expression in papillary thyroid carcinoma: a finding of potential diagnostic value in problematic cases of thyroid pathology

background: there are inter-observer disagreements between papillary thyroid carcinoma (ptc) with other follicular lesions of thyroid in aspect of diagnosis. cd56 is present on follicular epithelial cells of the normal thyroid. we evaluated the diagnostic value of cd56 expression in ptc, follicular thyroid lesions, and follicular thyroid neoplasms. materials and methods: seventythree cases diag...

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Absent CD56 expression in papillary thyroid carcinoma: A finding of potential diagnostic value in problematic cases of thyroid pathology

BACKGROUND There are inter-observer disagreements between papillary thyroid carcinoma (PTC) with other follicular lesions of thyroid in aspect of diagnosis. CD56 is present on follicular epithelial cells of the normal thyroid. We evaluated the diagnostic value of CD56 expression in PTC, follicular thyroid lesions, and follicular thyroid neoplasms. MATERIALS AND METHODS Seventy-three cases dia...

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Application of CD56, P63 and CK19 immunohistochemistry in the diagnosis of papillary carcinoma of the thyroid

Papillary carcinoma of the thyroid (PTC) is the commonest thyroid cancer. In the recent decades an obvious increase in the incidence of PTC has occurred. The pathological diagnosis of PTC is usually an easy diagnosis in the majority of cases. However since the introduction of follicular variant of PTC and the wide threshold range in interpretation of the clearly set pathological criteria for di...

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cd56, hbme-1 and cytokeratin 19 expressions in papillary thyroid carcinoma and nodular thyroid lesions

background: carcinomas of the thyroid follicular epithelium are the most common cancers of the endocrine system. in the diagnosis of thyroid nodules and tumors, the gold standard is histological evaluation. in cases which have morphological overlap,immunohistochemistry is needed for differential diagnosis. the purpose of this study is to investigate the expressions of cd56,hbme?1, cytokeratin 1...

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ژورنال

عنوان ژورنال: The International Journal of Biological Markers

سال: 2018

ISSN: 1724-6008,1724-6008

DOI: 10.1177/1724600817748538