DIAGNOSTIC SIGNIFICANCE OF S-100 PROTEIN, VIMENTIN AND HMB-45 MONOCLONAL ANTIBODIES IN SOME ORAL MELANOMAS
نویسندگان
چکیده
منابع مشابه
Diagnostic and Histogenetic Significance of S 100 Protein in Oral Diseases
S-100 protein, although originally isolated from brain tissue, has since been shown to be present in a wide variety of tissues and cell types. S 100 protein is present in cytoplasm and nucleoplasms of a wide array of cells. It's role in cell functioning is not clearly understood. S 100 protein is present in number of tumours occurring in maxillofacial region., including chondroid tumours, granu...
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Background: To study the role of epithelial-to-mesenchymal transition by Ecadherin and vimentin expression in precancerous and cancerous lesions of oral cavity and oropharynx and to predict invasiveness by the specific pattern of E-cadherin and vimentin expression. Methods: Biopsies/ specimens of oral cavity and oropharynx were evaluated for all premalignant lesions and invasive epithelial squa...
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Vimentin and S-100 protein expression was studied in the kidneys of adult sheep and goat using immunohistochemistry. Vimentin was detected in the podocytes, mesangial cells of the glomerulus, in the endothelium of renal capillaries and renal stromal cells. In collecting tubules, ducts and nerves of the renal papilla, S-100 protein was expressed.
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By immunizing mice with killed whole bacterial cells of Brucella abortus S (99), a panel of six hybridomas producing monoclonal antibodies (mAb) specific for the surface antigens of this bacterium were produced. ELISA was used to screen the hybridoma supernatants. Immunoblots of the cell extract indicated that three mAb were specific for S-LPS (Ba-1, Ba-2, Ba-3) and three others were reactive w...
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ژورنال
عنوان ژورنال: Egyptian Dental Journal
سال: 2016
ISSN: 2090-2360
DOI: 10.21608/edj.2016.95430