Diagnostic Role of Anti PGL-1 Antibody, Antigen 85-C and IP-10 (Interferon Gamma Inducible Protein) in Pediatric Leprosy
نویسندگان
چکیده
منابع مشابه
Biochemical characterization of a gamma interferon-inducible cytokine (IP-10)
An IFN-gamma-inducible protein, IP-10, has previously been described to belong to a gene family of chemotactic and mitogenic proteins, associated with inflammation and proliferation. Biochemical characterization of this predicted protein has been pursued through the development of polyclonal monospecific antisera to recombinant protein and synthetic peptides. These reagents establish that the I...
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BACKGROUND Chemokines are a large group of chemotactic cytokines that regulate and direct migration of leukocytes, activate inflammatory responses, and are involved in many other functions including regulation of tumor development. Interferon-gamma inducible-protein-10 (IP-10) is a member of the C-X-C subfamily of the chemokine family of cytokines. IP-10 specifically chemoattracts activated T l...
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Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease (IBD) affecting the colonic mucosa; it is of unknown etiology (Baumgart & Carding, 2007). UC clinically displays bloody diarrhea, abdominal pain and weight loss, and often leads to a severe outcome since the therapeutic approaches, including corticosteroid and 5-aminosalicylic acid, are not always successful in inducing ...
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Background:The premature termination of high producer clones, which will be killed due to cell proliferation and proteins production antagonism, is one of the basic drawback in recombinant proteins technology. Furtheremore, it is supposed some toxic proteins like interferon which we intended to clone and express, inhibit host cells’ proliferation. So, it is necessary to tightly control IFN-γ pr...
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Mycobacterial strains are potent inducers of cytokines/chemokines by mononuclear phagocytes, which constitute an important cellular component of the first line of defense in the innate immune system. Interferon (IFN)-γ-inducible protein (IP-10 or CXCL10) is a potent chemoattractant; however, little is known about the IP-10 profiles attributable to the Th1 regulation associated with active tuber...
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ژورنال
عنوان ژورنال: International Journal of Contemporary Medical Research [IJCMR]
سال: 2018
ISSN: 2454-7379,2393-915X
DOI: 10.21276/ijcmr.2018.5.9.2