Diagnostic markers for schizophrenia: do we actually know what we're looking for?

Diagnostic and therapeutic challenges for dermatologists: What shall we do when we don’t know what to do?

What shall we do when we have done everything we could for the diagnosis and treatment of a patient, but were not successful? What shall we do when there is no definite treatment for a patient? What shall we do when we have no diagnosis or treatment for a patient? Some useful suggestions are presented here to get rid of these situations.

Superior Capsule Reconstruction: What Do We Know?

The management of irreparable rotator cuff tears remains challenging. Since its introduction by Mihata in 2012, superiorcapsule reconstruction (SCR) has grown in popularity at an astonishingly rapid rate. The aim of this article is to providea comprehensive review of the available literature, in order to highlight what has so far been published on SCR,covering all aspects including biomechanica...

But What Do We Actually Know?

Knowledge bases such as Wikidata, DBpedia, YAGO, or the Google Knowledge Vault collect a vast number of facts about the world. But while quite some facts are known about the world, little is known about how much is unknown. For example, while the knowledge base may tell us that Barack Obama is the father of Malia Obama and Sasha Obama, it does not tell us whether these are all of his children. ...

Do We Know What We Do not Know? A Response to Celine Bonnet

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...