Diagnostic ileocolonoscopy: getting the basics right

Getting the basics right-staging in head and neck cancer

The cornerstone of oncology literature and therefore medical practice is the ability to compare outcomes of treatment modalities for different stages of cancer. The head and neck represents a complicated anatomical region with multiple tumour sites and sub-sites. Modern management necessitates accurate staging to allow meaningful discussion between all members of the multidisciplinary team. Var...

Getting Back to Basics

Advances in understanding basic developmental and physiological processes often have direct relevance to human disease. They provide insights into pathogenic mechanisms and reveal new pathways that can be exploited in diagnosis and the development of therapeutics.

Surviving the first hours in sepsis: getting the basics right (an intensivist's perspective).

Severe sepsis is a major cause of morbidity and mortality, claiming between 36 000 and 64 000 lives annually in the UK, with a mortality rate of 35%. International guidelines for the management of severe sepsis were published in 2004 by the Surviving Sepsis Campaign and condensed into two Care Bundles. In 2010, the Campaign published results from its improvement programme showing that, although...

Getting the basics right Contribution of Early Childhood Development to quality, equity and efficiency in education

Getting the Envisionment Right

The central component of commonsense reasoning about causdity is the envisionment: a description of the behavior of a phvsical system that is derived from its structural description by qualitative simulation. Two problems with creating the envisionmcnt are the qualitative representation of quentlty and the detection of previously-unsuspcctcd points ot qualitative change. The representation pres...