Diabetic mellitus type 1 in patient with beta major thalassemia (case report)

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Diabetic mellitus type 1 in patient with beta major thalassemia (case report)

Oxidative stress in pancreatic organ may occur in children with thalassemia. It is caused by the overloaded iron store which not bound by transferrin. This condition triggers apoptosis of pancreatic beta cell so that the production of insulin decelerated progressively. Finally, it results in glucose intolerance and the patient suffers from diabetic mellitus. Some studies conclude that the risk ...

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Diffuse Hepatic Calcifications in a Transfusion-Dependent Patient with Beta-Thalassemia: A Case Report

Hepatic calcification is usually associated with infectious, vascular, or neoplastic processes in the liver. We report the first case of beta-thalassemia major with isolated diffuse hepatic calcification in a 23 year old woman, who had been transfusion-dependent since the age of 6 months. She was referred to our center with a chief complaint of abdominal pain. Computed tomography scan of the ab...

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Watershed Infarct in Beta-Thalassemia Major Patient

Background. The mechanism of stroke in beta-thalassemia was reported previously as cardioembolic and hypercoagulable state. However, there is no report of watershed infarct in beta-thalassemia anemia. Method. We present an adult β-thalassemia major patient with manifest asymptomatic chronic left carotid occlusion who suffered watershed infarct. Result. In the presence of asymptomatic chronic le...

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Spontaneous Hemothorax in a Patient with Neurofibromatosis Type 1: A Case Report

Background: Neurofibromatosis type1 (NF-1) is a hereditary autosomal dominant disease that is accompanied by complications, such as benign and malignant tumors and vascular involvement, including pulmonary hypertension, artery stenosis, and pulmonary artery aneurysm. Spontaneous hemothorax is a rare and lethal complication of NF-1 due to vasculopathy as stenosis or aneurysmal modifications of l...

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ژورنال

عنوان ژورنال: International Journal of Pediatric Endocrinology

سال: 2013

ISSN: 1687-9856

DOI: 10.1186/1687-9856-2013-s1-p14