Dexmedetomidine-Associated Fever in a Critically Ill Obese Child

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Predictors of dexmedetomidine-associated hypotension in critically ill patients

BACKGROUND Dexmedetomidine is commonly used for sedation in the Intensive Care Unit (ICU), and its use may be associated with hypotension. We sought to determine predictors of dexmedetomidine-associated hypotension. METHODS Retrospective, single-center study of 283 ICU patients in four adults ICUs over a 12 month period. Univariate analyses were performed to determine factors associated with ...

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Population Pharmacokinetics of Dexmedetomidine in Critically Ill Patients

BACKGROUND AND OBJECTIVES Although the pharmacokinetics of dexmedetomidine in healthy volunteers have been studied, there are limited data about the pharmacokinetics of long-term administration of dexmedetomidine in critically ill patients. METHODS This population pharmacokinetic analysis was performed to quantify the pharmacokinetics of dexmedetomidine in critically ill patients following in...

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Significant Bradycardia in Critically Ill Patients Receiving Dexmedetomidine and Fentanyl

PURPOSE To report a case series of three patients who developed significant bradycardia while receiving the combination of dexmedetomidine and fentanyl for sedation and analgesia. MATERIALS AND METHODS This is a case series of patients obtained from a mixed medical, surgical, and cardiac ICU in a community teaching hospital. Three intubated patients receiving fentanyl and dexmedetomidine infu...

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Prolonged Infusion of Dexmedetomidine in Critically-ill Children.

OBJECTIVE To describe main indications, doses, length of infusion and side effects related to dexmedetomidine infusion. METHODS Observational and retrospective study evaluating dexmedetomidine use in pediatric intensive care unit. RESULTS 77 children received dexmedetomidine infusion longer than 6 hours for mechanical ventilation weaning (32.5%), post- neurosurgery and post-upper airway sur...

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Prolonged dexmedetomidine infusions in critically ill infants and children.

OBJECTIVE To present our institutional experience with prolonged dexmedetomidine (DEX) infusions in critically ill infants and children. DESIGN Retrospective medical chart review between January 1, 2007 and December 1, 2007. SETTING Tertiary care pediatric teaching hospital. PARTICIPANTS Infants and children (up to 18 years of age) who received DEX for a duration greater than 24 hours. ...

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ژورنال

عنوان ژورنال: The Journal of Pediatric Pharmacology and Therapeutics

سال: 2018

ISSN: 1551-6776

DOI: 10.5863/1551-6776-23.6.486