Dexamethasone Implant as Sole Therapy in Sympathetic Ophthalmia

Sympathetic Ophthalmia

Sympathetic ophthalmia (SO) is a rare bilateral, diffuse granulomatous panuveitis that occurs following penetrating trauma or intraocular surgery to one eye, the exciting eye. The fellow non-traumatized sympathizing eye also shows similar inflammatory response usually with mutton-fat KPs suggesting involvement of autoimmune response [1]. Though the time from ocular injury to onset of SO was sai...

[Biological therapy in sympathetic ophthalmia refractory to combined immunosuppressive treatment].

The objective of this communication is to report on the efficiency and advantages of the anti-TNF biological drug (adalimumab) in sympathetic ophthalmia (OS), bilateral panuveitis in which this treatment has not yet been described in world literature. A 40-year-old woman exhibiting sympathetic ophthalmia in the right eye with 2 years evolution after left eye retina detachment surgery failure. D...

Choroidal Neovascularization in Sympathetic Ophthalmia

A 49-year-old man presented after a ruptured globe repair of his left eye status post a bungee cord injury with decreased vision in his right eye six weeks after the trauma occurred. Visual acuities were 20/40 in the right eye and no light perception in the left eye. Intraocular pressures were 27 and 5, respectively. Slit lamp examination of the right eye revealed 1+ conjunctival injection, fin...

Twenty cases of sympathetic ophthalmia.

We reviewed the charts of 20 patients with sympathetic ophthalmia who were seen in the uveitis clinic at the Eye and Ear Infirmary within an 11-year period. Of these 20 patients 14 maintained 20/50 or better visual acuity in at least one eye. We found early enucleation to be associated with a better visual prognosis, possibly due to earlier diagnosis and faster, more aggressive therapy rather t...

Adalimumab for pediatric sympathetic ophthalmia.