Developments in Genetics

Developments and Expansions in Biology and Genetics

In the collective consciousness the word Genomics essentially means Human Genome Project (HGP). Yet while many scientists continue to speak of HGP as the most important tool proposed by molecular biologists, geneticists and... mathematicians to successfully complete the biomedical revolution of the twentieth century, there are many researchers who consider HGP a failure, a gigantic project whic...

Recent developments in cardiovascular genetics and genomics.

New developments in genetics of myositis.

PURPOSE OF REVIEW This article reviews the advances that have been made in our understanding of the genetics of the idiopathic inflammatory myopathies (IIM) in the past 2 years, with a particular focus on polymyositis, dermatomyositis and inclusion body myositis. RECENT FINDINGS Two large human leukocyte antigen (HLA) imputation studies have confirmed a strong association with the 8.1 ancestr...

Ethical implications of developments in genetics.

The overall purpose of this paper is to describe contemporary developments in genetics that have raised a variety of ethical problems. To do this, I will describe several of these developments, raise some of the thematic ethical issues to which they point, and describe some of the responses that have been made to them. Therefore, I wish to look at two broad problem areas related to the applicat...

Recent developments in the genetics of LDL deficiency.

PURPOSE OF REVIEW Inherited diseases of lipoprotein metabolism may give rise to marked hypocholesterolemia with low or absent levels of LDL, depending on the gene involved and mode of inheritance of the condition, together with the severity of the mutation or mutations present. In this review, we discuss the recent developments in the genetics of LDL deficiency. RECENT FINDINGS Carriers of a ...