Developmental Venous Anomalies Mimicking Neoplasm on 11C-Methionine PET and DSC Perfusion MRI

Atypical MR imaging perfusion in developmental venous anomalies.

Developmental venous anomalies (DVAs) are common variants of cerebral venous drainage that are typically incidental findings on contrast-enhanced MR imaging studies. We present four cases of asymptomatic DVAs that demonstrate increased cerebral blood flow, cerebral blood volume, mean transit time, and time to peak on perfusion MR images. Our study indicates that alterations in perfusion MR imag...

PET Imaging of 18F-FDG, 11C-methionine, 11C-flumazenil, and 11C-4DST in Progressive Multifocal Leukoencephalopathy

The use of positron emission tomography (PET) imaging in progressive multifocal leukoencephalopathy (PML) has rarely been reported. We herein report a set of PET images in a 63-year-old patient with PML. In PML lesions, the uptake of 18F-fluorodeoxyglucose, 11C-methionine, 11C-flumazenil, and [methyl-11C]4'-thiothymidine was decreased, increased, decreased, and unchanged, respectively. These re...

Mri of Fetal Developmental Anomalies

Simultaneous Perfusion MRI and FET-PET

PET imaging using radiolabelled amino acids tracer can specifically deliver valuable information about tumour extent, malignancy, and tumour recurrence. Perfusion MRI, which measures microcirculatory parameters such as cerebral blood flow (CBF) and cerebral blood volume (CBV), can precisely investigate vascular malformation, and help classify and grade brain tumours. In this study, FETPET and p...

Pathomechanisms of symptomatic developmental venous anomalies.

BACKGROUND AND PURPOSE Although it is generally accepted that developmental venous anomalies (DVAs) are benign vascular malformations, over the past years, we have seen patients with symptomatic DVAs. Therefore, we performed a retrospective study and a literature study to review how, when, and why DVAs can become clinically significant. METHODS Charts and angiographic films of 17 patients wit...