Development of prime–boost-type next-generation mucosal vaccines
نویسندگان
چکیده
منابع مشابه
Cancer vaccines: The next generation
1740-6773/$ 2005 Elsevier Ltd. All rights reserved. DOI: 10.1016/j.ddstr.2005.11.002 Section Editors: Tona Gilmer – GlaxoSmithKline, NC, USA Mike Luzzio – Pfizer Global Research and Development, USA The field of cancer vaccines is as vibrant as ever. Despite pessimism, considerable advances are being made on a regular basis. Success stories continue to be published and newer, exciting and, perh...
متن کاملNext-Generation Dengue Vaccines: Novel Strategies Currently Under Development
Dengue has become the most important arboviral infection worldwide with more than 30 million cases of dengue fever estimated to occur each year. The need for a dengue vaccine is great and several live attenuated dengue candidate vaccines are proceeding through clinical evaluation. The need to induce a balanced immune response against all four DENV serotypes with a single vaccine has been a chal...
متن کاملCost-effectiveness of next-generation vaccines: The case of pertussis.
Despite steady vaccination coverage rates, pertussis incidence in the United States has continued to rise. This public health challenge has motivated calls for the development of a new vaccine with greater efficacy and duration of protection. Any next-generation vaccine would likely come at a higher cost, and must provide sufficient health benefits beyond those provided by the current vaccine i...
متن کاملVaccine candidate discovery for the next generation of malaria vaccines
Although epidemiological observations, IgG passive transfer studies and experimental infections in humans all support the feasibility of developing highly effective malaria vaccines, the precise antigens that induce protective immunity remain uncertain. Here, we review the methodologies applied to vaccine candidate discovery for Plasmodium falciparum malaria from the pre- to post-genomic era. P...
متن کاملDesigning the next generation of vaccines for global public health.
Vaccine research and development are experiencing a renaissance of interest from the global scientific community. There are four major reasons for this: (1) the lack of efficacious treatment for many devastating infections; (2) the emergence of multidrug resistant bacteria; (3) the need for improving the safety of the more traditional licensed vaccines; and finally, (4) the great promise for in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Immunology
سال: 2019
ISSN: 1460-2377
DOI: 10.1093/intimm/dxz085