Development of nanostructured lipid carrier for dacarbazine delivery
نویسندگان
چکیده
منابع مشابه
Buparvaquone Nanostructured Lipid Carrier: Development of an Affordable Delivery System for the Treatment of Leishmaniases
Buparvaquone (BPQ), a veterinary drug, was formulated as nanostructured lipid carriers (NLC) for leishmaniases treatment. The formulation design addressed poor water solubility of BPQ and lack of human drug delivery system. The DSC/TG and microscopy methods were used for solid lipids screening. Softisan® 154 showed highest BPQ solubility in both methods. The BPQ solubility in liquid lipids usin...
متن کاملDevelopment and evaluation of nanostructured lipid carrier-based hydrogel for topical delivery of 5-fluorouracil
The aim of this study was to develop a nanostructured lipid carrier (NLC)-based hydrogel and study its potential for the topical delivery of 5-fluorouracil (5-FU). Precirol® ATO 5 (glyceryl palmitostearate) and Labrasol® were selected as the solid and liquid lipid phases, respectively. Poloxamer 188 and Solutol® HS15 (polyoxyl-15-hydroxystearate) were selected as surfactants. The developed lipi...
متن کامل1. Nanostructured lipid carrier for bioavailability enhancement
Nanostructred lipid carrier(NLC) is second generation drug carrier system having solid matrix at room temperature. This carrier system is made up of physiological, biodegradable and biocompatible lipid materials and surfactants and is accepted by regulatory authorities for application in different drug delivery system. The main objective of this review is to explore the role of NLCs system for ...
متن کاملNanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule
Nanostructured lipid carriers (NLCs) were employed to formulate a lipophilic drug into hydrophilic polymeric microneedles (MNs). Hyaluronic acid (HA) was selected as a hydrophilic and bioerodible polymer to fabricate MNs, and nile red (NR) was used as a model lipophilic molecule. NR-loaded NLCs were consolidated into the HA-based MNs to prepare NLC-loaded MNs (NLC-MNs). A dispersion of NLCs was...
متن کاملNanostructured lipid carriers (NLCs): A Novel based nano carrier for drug delivery and drug targeting
Aim: Nano structured lipid carriers (NLCs) contains solid and liquid lipids as the significant principle in the drug delivery system. This review is focused on various aspects involved in the preparation, structure, advantages, limitations, types, physiochemical characterization and wide pharmaceutical applications of SLN has been explored. Method:It is revealed that NLCs proved to be a promisi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Nano Letters
سال: 2015
ISSN: 2008-9295,2228-5326
DOI: 10.1007/s40089-015-0161-8