Development of Multinuclear Polymeric Nanoparticles as Robust Protein Nanocarriers
نویسندگان
چکیده
منابع مشابه
Development of multinuclear polymeric nanoparticles as robust protein nanocarriers.
One limitation of current biodegradable polymeric nanoparticles is their inability to effectively encapsulate and sustainably release proteins while maintaining protein bioactivity. Here we report the engineering of PLGA-polycation nanoparticles with a core-shell structure that act as a robust vector for the encapsulation and delivery of proteins and peptides. The optimized nanoparticles can lo...
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ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2014
ISSN: 0044-8249
DOI: 10.1002/ange.201404766