Development of Chiral Separation Using Chiral Stationary Phase Based on Polysaccharide Derivatives
نویسندگان
چکیده
منابع مشابه
Chiral recognition mechanisms of four β-blockers by HPLC with Amylose Chiral Stationary Phase
The high performance liquid chromatography (HPLC) enantioseparation of four β-blocking agents metoprolol, bisoprolol, propranolol and atenolol was performed on amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase using n-hexane-ethanol-diethylamine (DEA) as the mobile phase and related chiral recognition mechanisms were discussed. Enantiomeric separation of the fourβ-blockers was ...
متن کاملChiral recognition mechanisms of four β-blockers by HPLC with Amylose Chiral Stationary Phase
The high performance liquid chromatography (HPLC) enantioseparation of four β-blocking agents metoprolol, bisoprolol, propranolol and atenolol was performed on amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase using n-hexane-ethanol-diethylamine (DEA) as the mobile phase and related chiral recognition mechanisms were discussed. Enantiomeric separation of the fourβ-blockers was ...
متن کاملChiral separation of organic phosphonate compounds on cellulose CSP (chiral stationary phase) under reversed phase mode.
The enantiomers of fourteen O,O-dialkyl-2-benzyloxycarbonyl-aminoarylmethyl-phosphonates are directly separated on the tris(3,5-dimethylphenylcarbamate) cellulose column (Chiralcel OD-R) under reversed phase mode. The results of the chiral separation are different from the results obtained in the normal phase mode. The mobile phase plays an essential role in chiral discrimination when using Chi...
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Separation of the enantiomers of linezolid has been compared on derivatized cellulose and amylose chiral stationary phases (Chiracel OD and Chiralpak AD) with mixtures of hexane with 1-propanol, 2-propanol, or ethanol as mobile phases. It was found that use of a small amount of water as mobile phase additive can improve or prevent enantioseparation, depending on the column. The order of elution...
متن کاملHigh-performance Liquid Chromatography Separation of Glycerol Derivatives on a Chiral Stationary Phase
We report herein the separation of enantiomers of glycerol derivatives on a cellulose-modified chiral column (Chiracel OD) in normal-phase mode. This method is suitable for monitoring the progress of the reaction and for determination of the enantiomeric purity of products. The lipase Novozyme 435-catalysed enantioselective hydrolysis of 1-O-benzyl-2,3di-O-octanoyl-rac-glycerol has been shown t...
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ژورنال
عنوان ژورنال: Oleoscience
سال: 2016
ISSN: 1345-8949,2187-3461
DOI: 10.5650/oleoscience.16.381