Development of BOLD signal hemodynamic responses in the human brain
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چکیده
منابع مشابه
Development of BOLD signal hemodynamic responses in the human brain
In the rodent brain the hemodynamic response to a brief external stimulus changes significantly during development. Analogous changes in human infants would complicate the determination and use of the hemodynamic response function (HRF) for functional magnetic resonance imaging (fMRI) in developing populations. We aimed to characterize HRF in human infants before and after the normal time of bi...
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Cerebral hemodynamic responses to brief periods of neural activity are delayed and dispersed in time. The specific shape of these responses is of some importance to the design and analysis of blood oxygenation level-dependent (BOLD), functional magnetic resonance imaging (fMRI) experiments. Using fMRI scanning, we examine here the characteristics and variability of hemodynamic responses from th...
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Functional MRI of the spinal cord is challenging due to the small cross section of the cord and high level of physiological noise. Though blood oxygenation level-dependent (BOLD) contrast has been used to study specific responses of the spinal cord to various stimuli, it has not been demonstrated using a controlled stimulus. In this paper, we use hypercapnic manipulation to study the sensitivit...
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Hemodynamic scaling of fMRI-BOLD signal amplitude in normal aging
Introduction: Vascular reactivity and resting cerebral blood flow (CBF) levels lead to inter-subject variability in functional magnetic resonance imaging (fMRI) studies using the Blood Oxygen Level Dependent (BOLD) contrast to a neural task. This variability is exacerbated in an aging population [1]. Hemodynamic scaling using Resting State Fluctuation Amplitude (RSFA) or Breath hold (BH) can mi...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2012
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2012.06.054