Development of acquired immunity to Salmonella

Acquired immunity to malaria.

Naturally acquired immunity to falciparum malaria protects millions of people routinely exposed to Plasmodium falciparum infection from severe disease and death. There is no clear concept about how this protection works. There is no general agreement about the rate of onset of acquired immunity or what constitutes the key determinants of protection; much less is there a consensus regarding the ...

Hinders Development of Acquired Immunity Successful Treatment of Bacterial Infection

Micro-balancing innate immunity to Salmonella.

MicroRNAs are 19–24 nt-long RNAs that post-transcriptionally regulate eukaryotic gene expression. Beside their important roles in patterning and development, miRNAs also orchestrate responses to pathogen infections. In this issue of The EMBO Journal, Schulte et al (2011) investigate the miRNA response of mammalian cells to the intracellular bacterium Salmonella. They find that Salmonella trigge...

THE ROLE OF B-CELLS IN THE DEVELOPMENT OF IMMUNITY TO CRYPTOSPORIDIUM INFECTION

Studies have shown that symptomatic improvement of cryptosporidiosis in immunocompromised patients is possible following treatment with" hyperimmune" colostrum containing anti-sporozoite antibodies from cattle immunized with Cryptosporidium parvum antigens. The contribution to immunity of antibodies developed during Cryptosporidium infection is unclear, however. Previously, we showed that ...

Innate and acquired immunity

• The cells of the immune system are divided into lymphoid and myeloid lineages. The former include T lymphocytes and their subsets identified by CD markers, B lymphocytes and natural killer (NK) cells. The myeloid lineage includes the neutrophils, eosinophils and basophils as well as the monocyte/ macrophage series and platelets. • Innate immunity depends on physical, physiological and chemica...