Development of a new photocrosslinkable biodegradable bioadhesive
نویسندگان
چکیده
منابع مشابه
Development of a new photocrosslinkable biodegradable bioadhesive.
Adhesives provide a needle-free method of wound closure and do not require local anaesthetics. Polymeric adhesives have been used for about 3 decades for joining several tissues of the organism. Also, they can accomplish other tasks, such as haemostasis and the ability to seal air leakages and have the potential to serve as delivery systems. PCL was modified with 2-isocyanatoethylmethacrylate t...
متن کاملDevelopment of bioactive photocrosslinkable fibrous hydrogels.
Three-dimensional (3D) fibrous hydrogels were fabricated by blending two photoactive polymers, poly(ethylene glycol) diacrylate (PEGDA) and poly(vinyl alcohol) (PVA), and the resulting solution was electrospun. PEGDA is a commonly used hydrogel material for tissue engineering applications since its interaction with cells can be tuned by crosslinking in a variety of bioactive molecules including...
متن کاملMechanically robust and bioadhesive collagen and photocrosslinkable hyaluronic acid semi-interpenetrating networks.
In this work, we present a class of hydrogels that leverage the favorable properties of the photo-cross-linkable hyaluronic acid (HA) and semi-interpenetrating collagen components. The mechanical properties of the semi-interpenetrating-network (semi-IPN) hydrogels far surpass those achievable with collagen gels or collagen gel-based semi-IPNs. Furthermore, the inclusion of the semi-interpenetra...
متن کاملDevelopment of a Curcumin Bioadhesive Monolithic Tablet for Treatment of Vaginal Candidiasis
The present investigation was designed to formulate a natural tablet for the treatment of vaginal candidiasis in order to eliminate side effects that are caused by existing antifungal drugs. Curcumin has promising antifungal activity in comparison with the existing azole antifungal drugs. Bioadhesive curcumin vaginal tablets were prepared by direct compression with different ratios of biadhesiv...
متن کاملDevelopment of a Curcumin Bioadhesive Monolithic Tablet for Treatment of Vaginal Candidiasis
The present investigation was designed to formulate a natural tablet for the treatment of vaginal candidiasis in order to eliminate side effects that are caused by existing antifungal drugs. Curcumin has promising antifungal activity in comparison with the existing azole antifungal drugs. Bioadhesive curcumin vaginal tablets were prepared by direct compression with different ratios of biadhesiv...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2008
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2007.10.026