Development, Maturation, and Transdifferentiation of Cardiac Sympathetic Nerves
نویسندگان
چکیده
منابع مشابه
Development, maturation, and transdifferentiation of cardiac sympathetic nerves.
The heart is electrically and mechanically controlled as a syncytium by the autonomic nervous system. The cardiac nervous system comprises the sympathetic, parasympathetic, and sensory nervous systems that together regulate heart function on demand. Sympathetic electric activation was initially considered the main regulator of cardiac function; however, modern molecular biotechnological approac...
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Although several cytokines and neurotrophic factors induce sympathetic neurons to transdifferentiate into cholinergic neurons in vitro, the physiological and pathophysiological roles of this remain unknown. During congestive heart failure (CHF), sympathetic neural tone is upregulated, but there is a paradoxical reduction in norepinephrine synthesis and reuptake in the cardiac sympathetic nervou...
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Simultaneous recording of activity in the vagal and sympathetic supplies to the heart has revealed that in reflexly and centrally evoked activity these two "antagonists" do not necessarily change action reciprocally. Coactivation occurs in chemoreceptor reflexes and related reactions, upon stretching of the sinoatrial nodal region of the right atrium and when certain hypothalamic regions are st...
متن کاملA Functional Study of Distribution of Cardiac Sympathetic Nerves.
RANDALL, WALTER C., DONALD V. PRIOLA, AND RICHARD H. ULMER. A functional study of distribution of cardiac sympathetic nerves. Am. J. Physiol. 205(6): 1227-1231. I g63.-In dogs with unilaterally sympathectomized hearts, the remaining intact stellate ganglion was electrically stimulated I 4-58 days following sympathectomy. Pressures were simultaneously recorded from all four chambers of the heart...
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Background: Uterine natural killer (uNK) cells are the most abundant leukocytes in pre-implantation endometrium and early pregnancy deciduas in humans and rodents. They are associated with structural changes in maternal spiral arteries but regulation of their re-cruitment and activation is incompletely understood. The major subpopulation of uNK cells in humans expresses CD56, the neural cell ad...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2012
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.111.257253