Development and in Vitro Evaluation of Ibuprofen Mouth Dissolving Tablets Using Solid Dispersion Technique

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Development and in vitro evaluation of ibuprofen mouth dissolving tablets using solid dispersion technique.

The aim of present study was to prepare and evaluate mouth dissolving tablets of ibuprofen (IBU). Ternary solid dispersion (SD) of IBU was prepared using PEG 4000 as carrier and Tween 80 as surfactant. The SD formulations were prepared by solvent evaporation and melt solvent method by varying ratio of PEG 4000. Different weight ratio of carrier, drug and surfactant 5 : 5 : 1, 10 : 5 : 1, 25 : 5...

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In Vitro-in Vivo Evaluation of Fast-dissolving Tablets Containing Solid Dispersion of Oxcarbazepine

Objective: Investigation of in vitro/in vivo behaviour of fast-dissolving tablets containing solid dispersions of oxcarbazepine is the focus of the present research work. Methods: The effect of various hydrophilic polymers on the aqueous solubility of oxcarbazepine was studied. Polyethylene glycol 6000 carrier was selected and solid dispersions were prepared by various methods. A total of nine ...

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Formulation Evaluation of Mouth Dissolving Tablets of Fenofibrate Using Sublimation Technique

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 2010

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.58.1037