DEVELOPMENT AND CHARACTERIZATION OF PRECIROL ATO 88 BASE IN NANOSTRUCTURED LIPID CARRIERS (NLC) FORMULATION WITH THE PROBE SONICATION METHOD

Influence of process parameters on properties of Nanostructured Lipid Carriers (NLC) formulation.

Nanostructured lipid carriers (NLC) are stable colloidal formulations with notable advantages for drug delivery systems. Thanks to their physicochemical stability, biocompatibility, biodegradability and controlled drug release, they have received increasing attention for the last several years. The aim of the study was to prepare and characterize nanostructured lipid carriers (NLC). Both, the e...

Formulation and in vitro characterization of domperidone loaded solid lipid nanoparticles and nanostructured lipid carriers

BACKGROUND AND THE PURPOSE OF THE STUDY Domperidone (DOM) is a dopamine- receptor (D(2)) antagonist, widely used in the treatment of motion-sickness. The pharmacokinetic parameters of DOM make it a suitable candidate for development of Solid Lipid Nanoparticle (SLN) and Nanostructured Lipide Carrier (NLC). The purpose of the present investigation was to prepare and evaluate DOM loaded solid lip...

Itraconazol-Loaded Nanostructured Lipid Carriers (NLC) for Pulmonary Application

Formulation and Characterization of [6]-gingerol Loaded Nanostructured Lipid Carrier (nlc)

Nanostructured lipid carrier (NLC) is the blend of solid lipid, liquid lipid and suitable surfactant for the purpose of encapsulated poorly water soluble drugs. [6]-gingerol is the main bioactive compound in Zingiber officinale, widely known as ginger in Malaysia. Zingiber officinale extract has been discovered to have anti-oxidant, anti-inflammatory, and anti-microbial effects to human body. T...

Formulation Optimization and Evaluation of Nanostructured Lipid Carriers Containing Valsartan

Nanostructured lipid carriers (NLCs), a lipid based colloidal carrier system, offer many advantages such as increase the solubility, improves the bioavailability and therapeutic efficacy. Incorporation of liquid lipid can improve the drug loading capacity in the NLCs. Valsartan is an antihypertensive drug with low oral bioavailability ranging from 10-35% because of poor solubility and extensive...