Determination of Strychnine in Nux Vomica by Paper Chromatography

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Poisoning by Strychinos Nux Vomica

IjOHAKNO, jih adult male, was brought to the dispensary, Aska, at 7-30 a.m., on the 17th February 1889, with the following symptoms: Giddiness of head ; a sensation of swimming of the whole body; feeling of numbness in the trunk and more markedly in the lower extremities ; dryness of throat ; slight injection of the ocular conjunctivae; heaviness of head ; occasional backward jerking of the hea...

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A rare case of strychnine poisoning by consumption of Strychnos nux- vomica leaves

Strychnine is one of the oldest poisons known to man. The source of this potent toxin is the Strychnos nux-vomica plant, which actually contains two distinct alkaloidsstrychnine and brucine. Although principally found in the seeds, these alkaloids can be isolated in varying concentrations from virtually all parts of the plant including the bark, leaves and roots[1]. Once consumed, strychnine pr...

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Tlc – Spectrophotometric Analysis of Strychnine and Brucine from the Ayurvedic Pills of Nux Vomica

Ayurvedic preparations claim on their label only the quantity of crude drugs and not the quantity of active ingredients present therein. So work was taken up to find the percentage of strychnine and brucine from Ayurvedic pills of Nux vomica powder by TLC spectrophotometric analysis, which study has not been reported earlier. However, the literature survey only revealed the following work.

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Pharmacological evaluation of total alkaloids from nux vomica: effect of reducing strychnine contents.

The aim of the study was to investigate the possibility of improving the therapeutic efficacy of the total alkaloid fraction (TAF) extracted from processed nux vomica by reducing the strychnine contents. Most strychnine was removed from TAF to obtain the modified total alkaloid fraction (MTAF). The toxicity and pharmacokinetics of TAF and MTAF were further investigated and compared besides thei...

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Nux-Vomica Poisoning of an Habitueé

Sib,?The following account of fatal poisoning' of Nux Vomica habituee may prove interesting to your readers :? Madiga Chennoogadoo, a sweeper by occupation, aged about 25, well built, was brought to the Badval Civil Dispensary, at 11 A.M. on the 12th of March last, with the following history :?Occasionally he had been in the habit of eating two seeds of Strychnos Nux Vomica at a time to get him...

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ژورنال

عنوان ژورنال: Nature

سال: 1958

ISSN: 0028-0836,1476-4687

DOI: 10.1038/182742a0