Determination of brucella immunoglobulin G agglutinating antibody titer with dithiothreitol

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Determination of brucella immunoglobulin G agglutinating antibody titer with dithiothreitol.

The routine brucella agglutination test measures both immunoglobulin M (IgM) and IgG brucella antibody titers; however, only an elevated IgG titer is significant for differentiating active from inactive disease in patients with symptoms lasting 3 or more weeks. The IgG antibody titer can be determined by treating the serum wih 2-mercaptoethanol to inactivate the IgM brucella antibodies while le...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 1981

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.14.1.24-25.1981