Determination of Benzalkonium Chloride in Ophthalmic Solutions by Stability-Indicating HPLC Method: Application to a Stability Study

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Determination of Benzalkonium Chloride in Ophthalmic Solutions by Stability-Indicating HPLC Method: Application to a Stability Study

Article history: Received on: 29/02/2016 Revised on: 15/03/2016 Accepted on: 06/04/2016 Available online: 28/05/2016 A simple HPLC method for determination of Benzalkonium chloride in various ophthalmic solutions was developed. The chromatographic analysis was achieved using CN column (250 mm, 4.6 mm i.d., 5 μm) with isocratic mobile phase consisting of acetonitrile phosphate buffer (pH 5.5; 0....

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ژورنال

عنوان ژورنال: Journal of Applied Pharmaceutical Science

سال: 2016

ISSN: 2231-3354

DOI: 10.7324/japs.2016.60513