منابع مشابه
Comparison of sublingual tablets with nitroglycerin complexed with beta-cyclodextrin or titrated with crosspovidone--technological approach.
Fast disintegrating sublingual tablets containing nitroglycerin either complexed with beta-cyclodextrin (NTG-CD) or titrated with crosspovidone (NTG-CP) were prepared using Starch 1500 or StarLac as disintegrants. Regarding disintegration time and stability of the active substance Starch 1500 was more appropriate for NTG-CD while for NTG-CP StarLac was suitable. Stability of NTG was better in N...
متن کاملEffects of Nitroglycerin
Twenty-three patients exhibiting coronary insufficiency on exercise have been studied at rest and at exercise prior to and following sublingual administration of nitroglycerin. The most consistent and marked effect of nitroglycerin was the reduction in pulmonary artery pressure, total pulmonary resistance, and right ventricular work at rest and during exercise. Our patients were grouped accordi...
متن کاملEffects of Sublingual Nitroglycerin
I. Moss AJ, Rivers RJ Jr, Griffith LSC, Carmel JA, Millard EB Jr: Transvenous left atrial pacing for the control of recurrent ventricular fibrillation. N Engl J Med 278: 928, 1968 2. Moss AJ, Rivers RJ Jr, Cooper M: Long-term pervenous atrial pacing from the proximal portion of the coronary vein. JAMA 209: 543, 1969 3. Kramer DH, Moss AJ: Permanent pervenous atrial pacing from the coronary vein...
متن کاملFailure of Intracoronary Nitroglycerin
Relief of angina by nitroglycerine has been attributed to two possible mechanisms: (1) Increase in myocardial blood supply by direct acton of the drug on the coronary arteries. (2) Reduction in myocardial oxygen demand by action of the drug on the systemic circulation. Sublingual application of nitroglycerin in previous studies did not allow the ruling out of the operation of either or both mec...
متن کاملEffect of Intravenous Nitroglycerin
This study was performed to determine whether nitroglycerin (NG) can increase collateral flow to ischemic myocardium and reduce ultimate infarct size. Permanent occlusion of the mid-circumflex coronary artery was produced in 43 previously instrumented conscious dogs and within 3 minutes, 6-hour intravenous infusions were begun of saline (controls, n = 18), NG in doses to reduce mean arterial pr...
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ژورنال
عنوان ژورنال: The Journal of the American Pharmaceutical Association (1912)
سال: 1914
ISSN: 0898-140X
DOI: 10.1002/jps.3080030126