Detection of group a streptococcal pharyngitis by quantitative PCR

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Detection of group a streptococcal pharyngitis by quantitative PCR

BACKGROUND Group A streptococcus (GAS) is the most common bacterial cause of sore throat. School-age children bear the highest burden of GAS pharyngitis. Accurate diagnosis is difficult: the majority of sore throats are viral in origin, culture-based identification of GAS requires 24-48 hours, and up to 15% of children are asymptomatic throat carriers of GAS. The aim of this study was to develo...

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Group A streptococcal pharyngitis

The group A Streptococcus is the most common bacterial cause of pharyngitis. Although most cases of streptococcal pharyngitis are managed by primary care providers, the otolaryngologist is often consulted to assist in the management of patients with persistent sore throat, chronic streptococcal carriage, recurrent streptococcal pharyngitis, or complications of streptococcal infection. This arti...

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Treatment strategies for group A streptococcal pharyngitis.

In the recent, nicely done study by Needham et al. (2) concerning the impact of a rapid group A streptococcal antigen assay on physician usage of appropriate antibiotics, there are two areas of concern. (i) In the abstract, the authors state that if the rapid antigen test alone had guided therapeutic choice, an appropriate course of antibiotics would have been prescribed for 95% of the patients...

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Use of PCR for Diagnosis of Group A Streptococcal Pharyngitis in the United States, 2011–2015

Background. Current susceptibility testing recommendations for β-hemolytic streptococci outline testing for clindamycin resistance, including inducible resistance by a positive D-zone phenotype. However, few studies describe the prevalence of clindamycin resistance among invasive GCS and GGS organisms. This study aims to describe the prevalence of clindamycin resistance among GCS/GGS compared w...

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comparison of clinical findings and rapid streptococcal antigen detection test in the diagnosis of group a streptococcal (gas) pharyngitis

conclusions although lap had good performance in early diagnosis of gas, a combination of clinical findings, including tonsillar exudates, petechiae with results of rapid antigen test or culture is necessary for clinician judgment. throat culture is the gold standard test for detecting group a streptococcal infection, but rapid test is a good replacement for culture. objectives the aim of this ...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2013

ISSN: 1471-2334

DOI: 10.1186/1471-2334-13-312