Detection and prevalence of inducible clindamycin resistance in staphylococci
نویسندگان
چکیده
منابع مشابه
Inducible clindamycin resistance in staphylococci isolated from clinical samples.
This study aimed to determine the levels of the macrolides-lincosamides-streptogramins B (MLS(B)) resistance phenotype of Staphylococcus aureus and coagulase-negative staphylococci (CNS) isolates from clinical samples. A total of 521 strains of staphylococci, comprising 230 S. aureus and 291 CNS isolates from various clinical samples, were identified by conventional methods. The double-disc tes...
متن کاملDistribution of erm genes and low prevalence of inducible resistance to clindamycin among staphylococci isolates.
INTRODUCTION Resistance to macrolides, lincosamides and streptogramins B (MLS(B) antibiotics) in staphylococci may be due to modification in ribosomal target methylase encoded by erm genes. The expression of MLS(B) resistance lead to three phenotypes, namely constitutive resistance (cMLS(B)), inducible resistance (iMLS(B)), and resistance only to macrolides and streptogramins B (MS(B)). The iML...
متن کاملInducible clindamycin resistance among clinical isolates of Staphylococci.
INTRODUCTION Clinical failure of clindamycin therapy has been reported due to multiple mechanisms that confer resistance to macrolide, lincosamide and streptogramin antibiotics. This study was undertaken to detect the presence of inducible clindamycin resistance among clinical isolates of staphylococci. MATERIALS AND METHODS The detection of inducible clindamycin resistance was performed by D...
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Clindamycin has been used successfully to treat pneumonia and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. However, inducible clindamycin resistance has been described as a cause of treatment failure of such infections. A total of 159 staphylococcal isolates from different clinical specimens from burn patients in Tripoli Burn Center were tested for inducible cli...
متن کاملprevalence of clindamycin inducible resistance in staphylococcus aureus and coagulase-negative staphylococci using d-test: a short report
background and objective: the d-test is performed by placing clindamycin and erythromycin impregnated disks at a standard distance on the agar plate then looking for the flattening of inhibition zone around the clindamycin disk. a positive d-test indicates clindamycin inducible resistance and also predicts treatment failure possibility of this antibiotic in clinic. prevalence of staphylococcal ...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 2007
ISSN: 0022-2615,1473-5644
DOI: 10.1099/jmm.0.46761-0