Detailed Map of Oxidative Post-Translational Modifications of Human P21Ras Using Fourier Transform Mass Spectrometry
نویسندگان
چکیده
منابع مشابه
Detailed map of oxidative post-translational modifications of human p21ras using Fourier transform mass spectrometry.
P21ras, the translation product of the most commonly mutated oncogene, is a small guanine nucleotide exchange protein. Oxidant-induced post-translational modifications of p21ras including S-nitrosation and S-glutathiolation have been demonstrated to modulate its activity. Structural characterization of this protein is critical to further understanding of the biological functions of p21ras. In t...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2006
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac060525v