DeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals
نویسندگان
چکیده
منابع مشابه
DeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals
The secretion of insulin by pancreatic islet β-cells plays a pivotal role in glucose homeostasis and diabetes. Recent work suggests an important role for SUMOylation in the control of insulin secretion from β-cells. In this paper we discuss mechanisms whereby (de)SUMOylation may control insulin release by modulating β-cell function at one or more key points; and particularly through the acute a...
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ژورنال
عنوان ژورنال: Biomolecules
سال: 2012
ISSN: 2218-273X
DOI: 10.3390/biom2020269