منابع مشابه
Design of Targeted B Cell Killing Agents
B cells play an important role in the pathogenesis of both systemic and organ-specific autoimmune diseases. Autoreactive B cells not only produce autoantibodies, but also are capable to efficiently present specific autoantigens to T cells. Furthermore, B cells can secrete proinflammatory cytokines and amplify the vicious process of self-destruction. B cell-directed therapy is a potentially impo...
متن کاملTargeted Killing
The purpose of this paper is to provide a philosophical defense for targeted killings in the wars against terror. The paper argues that if one accepts the moral legitimacy of the large-scale killing of combatants in conventional (what are soon to be called "old-fashioned") wars, one cannot object — on moral grounds — to the targeted killing of terrorists in wars against terror. If one rejects t...
متن کاملB cell targeted therapies
Although the precise pathogenesis of rheumatoid arthritis (RA) remains unclear, many cell populations, including monocytes, macrophages, endothelial cells, fibroblasts and B cells, participate in the inflammatory process. Ongoing research continues to evaluate the critical roles played by B cells in sustaining the chronic inflammatory process of RA. These findings have contributed to the develo...
متن کاملIsrael’s Policy of Targeted Killing
ince the eruption of the second intifada in September 2000, Israel has openly pursued a policy of targeted killing. The Israelis have identified, located, and then killed alleged Palestinian terrorists with helicopter gunships, fighter aircraft, tanks, car bombs, booby traps, and bullets. Approximately eighty Palestinian militants and about fifty innocent bystanders have been killed through fal...
متن کاملComparative killing rates of fluoroquinolones and cell wall-active agents.
Killing rates of fluoroquinolones, beta-lactams, and vancomycin were compared against Enterobacteriaceae, Staphylococcus aureus, pneumococci, streptococci, and Enterococcus faecalis. The times required for fluoroquinolones to decrease viability by 3 log(10) were 1.5 h for Enterobacteriaceae, 4 to 6 h for staphylococci, and >/=6 h for streptococci and enterococci. Thus, the rate of killing by fl...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0020991