Design, Development and in vitro Assessment of Flurbiprofen Microemulsion Gel for Transdermal Drug Delivery

نویسندگان

چکیده

The aim of current research is to develop flurbiprofen microemulsion gel for transdermal delivery. To prepare a oil, surfactant and co-surfactant selection one the important criteria. Selected different ratios oil mixture using ternary phase diagram. Based on results physicochemical properties, we have optimized formulation. formulation incorporated into carbopol P 934 base. In vitro diffusion drug release shown maximum (98.6% in 12hrs) prepared than marketed (60.5% 16 hrs).

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ژورنال

عنوان ژورنال: Journal of pharmaceutical research international

سال: 2022

ISSN: ['2456-9119']

DOI: https://doi.org/10.9734/jpri/2022/v34i46a36381