DESIGN AND INVITRO CHARACTERIZATION OF METFORMIN LOADED RESEALED ERYTHROCYTES
نویسندگان
چکیده
منابع مشابه
Resealed Erythrocytes: an Advanced Review
Erythrocytes are the most abundant cells in the human body (~5.4 million cells/mm blood in a healthy male and ~ 4.8 million cells/mm blood in a healthy female) having potential carrier capabilities for the delivery of drugs and drug loaded microspheres. Drug-loaded carrier erythrocytes are prepared simply by collecting blood samples from the organism of interest, separating erythrocytes from pl...
متن کاملResealed Erythrocytes - As a Carrier
Amongst various carriers explored for target oriented drug delivery, vesicular, microparticulate and cellular carriers meet several criteria rendering them useful in clinical applications. Lymphocytes, leukocytes, platelets, granulocytes and erythrocytes have been proposed as a cellular carrier. Erythrocytes, also known as red blood cells, and have been the most extensively investigated and fou...
متن کاملCharacterization of the complement sensitivity of calcium loaded human erythrocytes.
A deficiency of membrane proteins having a glycosylphosphatidylinositol (GPI) anchor is characteristic of the erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH) and is currently believed to be the basis for the enhanced susceptibility to lysis by activated complement observed in these cells. Our recent observation that GPI-anchored proteins are preferentially lost into membrane vesicles ...
متن کاملResealed Erythrocytes: Potential Carrier for Delivery of Drugs
S. K. Shyama*, K. S. Rathore, Roshan Keshri B. N. Institute of Pharmaceutical Sciences, Udaipur Rajasthan 313001 Erythrocytes, also known as red blood cells, have been extensively studied for their potential carrier capabilities for the delivery of drugs and drug-loaded microspheres. Such drug-loaded erythrocytes are prepared simply by collecting blood samples from the organism of interest, sep...
متن کاملResealed Erythrocytes as a Potential Drug Carrier System
Novel drug delivery system has been introduced to overwhelm the drawback of fluctuating drug levels associated with conventional dosage forms. Out of various cellular carrier systems, erythrocytes (red blood cells, RBC) have been the most widely investigated and found to possess great potential for the delivery of drugs and drug-loaded microspheres. These cellular carriers, having remarkable bi...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2017
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2017.v10i4.16636