Dependence on temperature and guanine-cytosine content of bubble length distributions in DNA

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Dependence on temperature and guanine-cytosine content of bubble length distributions in DNA.

We present numerical results on the temperature dependence of the distribution of bubble lengths in DNA segments of various guanine-cytosine (GC) concentrations. Base-pair openings are described by the Peyrard-Bishop-Dauxois model and the corresponding thermal equilibrium distributions of bubbles are obtained through Monte Carlo calculations for bubble sizes up to the order of a hundred base pa...

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ژورنال

عنوان ژورنال: The Journal of Chemical Physics

سال: 2009

ISSN: 0021-9606,1089-7690

DOI: 10.1063/1.3149859