DEPARTMENT OF BIOCHEMISTRY, SCHOOE OF MEDICIN
نویسندگان
چکیده
منابع مشابه
Department of Biochemistry & Molecular Biology
Alkbh1 is a human homolog of the Escherichia coli AlkB protein that directs DNA repair by removing alkylation damage to DNA bases. While the in vivo role of Alkbh1 is still unknown, the protein was recently shown to possess abasic site lyase activity in vitro and to cleave abasic sites according to a betaelimination mechanism. Surprisingly, Alkbh1 forms a covalent adduct to the 5?-DNA product. ...
متن کاملDepartment of Biochemistry & Molecular Biology
Poster Presentations Wednesday, April 11, 2007 1 floor of the Biochemistry Building 3:00 – 5:00 p.m.
متن کاملDepartment of Biochemistry & Molecular Biology
Activation-Induced Deaminase (AID) protein functions in class switch recombination and somatic hypermutation in mammalian cells. The AID protein deaminates cytidine sites in single stranded DNA. We designed and constructed an expression plasmid that encodes AID as a recombinant fusion protein. Our construct includes an N-terminal maltose binding protein as a solubility and expression tag follow...
متن کاملDepartment of Biochemistry and Molecular Biology I, School of Biology,
Cannabinoids, the active components of marijuana and their derivatives, induce tumor regression in rodents (8). However, the mechanism of cannabinoid antitumoral action in vivo is as yet unknown. Here we show that local administration of a nonpsychoactive cannabinoid to mice inhibits angiogenesis of malignant gliomas as determined by immunohistochemical analyses and vascular permeability assays...
متن کاملLabs chief Peter Kim to join Department of Biochemistry
In genetically susceptible people, narcolepsy can sometimes be triggered by a similarity between a region of a protein called hypocretin and a portion of a protein from the pandemic H1N1 virus, according to a new study by researchers at the School of Medicine. The study provides some of the most compelling cellular and molecular evidence to date for a scientific concept known as “molecular mimi...
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ژورنال
عنوان ژورنال: The KITAKANTO Medical Journal
سال: 1960
ISSN: 0023-1908,1883-6135
DOI: 10.2974/kmj1951.10.4_522