DENTIN SEBAGAI BAHAN CANGKOK TULANG DALAM PERAWATAN REGENERASI JARINGAN PERIODONTAL: SEBUAH TINJAUAN

Introduction: Alveolar bone is the most affected of periodontal diseases. Bone grafts such as autograft, allograft, xenograft and, alloplastic often are used, but they have limitations. So, graft still a major problem that continues to inspire design new materials. The purpose this article review clinical and biologic function, advantages, disadvantages dentin an autograft allograft in therapy. Review: Autograft gold standard augmentation because its excellent osteoinductivity osteoconductivity. mineralized tissues almost similar chemical compositions. Dentin matrix obtained from tooth has be demineralized before using it material. consists 18% collagen, 2% noncollagenous proteins, 70% hydroxyapatite, 10% body fluid. Matrix repository for growth factors, Morphogenetic Proteins (BMP), Transforming Growth Factor-β (TGF-β), Insulin-like Factor (IGF), Basic Fibroblast (bFGF). Demineralized (DDM) highly biocompatible can support cell proliferation, enhances remodeling capabilities leads absence antigenicity. DDM was further suggested ideal scaffold stem cells therefore could recycled innovative biomaterial. Conclusion: present results indicate materials used graft.