Dentate nucleus stimulation for essential tremor
نویسندگان
چکیده
منابع مشابه
Defective dentate nucleus GABA receptors in essential tremor.
The development of new treatments for essential tremor, the most frequent movement disorder, is limited by a poor understanding of its pathophysiology and the relative paucity of clinicopathological studies. Here, we report a post-mortem decrease in GABA(A) (35% reduction) and GABA(B) (22-31% reduction) receptors in the dentate nucleus of the cerebellum from individuals with essential tremor, c...
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BACKGROUND There is increasing interest in the use of non-invasive brain stimulation to characterize and potentially treat essential tremor (ET). Studies have used a variety of stimulation coils, paradigms, and target locations to make these observations. We reviewed the literature to compare prior studies and to evaluate the rationale and the methods used in these studies. METHODS We perform...
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OBJECT Deep brain stimulation (DBS) performed under general anesthesia ("asleep" DBS) has not been previously reported for essential tremor. This is in part due to the inability to visualize the target (the ventral intermediate nucleus [VIM]) on MRI. The authors evaluate the efficacy of this asleep technique in treating essential tremor by indirect VIM targeting. METHODS The authors retrospecti...
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BACKGROUND Orthostatic tremor (OT) was first described in 1977. It is characterized by rapid tremor of 13-18 Hz and can be recorded in the lower limbs and trunk muscles. OT remains difficult to treat, although some success has been reported with deep brain stimulation (DBS). CASE REPORT We report a 68-year-old male with OT who did not improve significantly after bilateral thalamic stimulation...
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BACKGROUND The preferred surgical target for the treatment of Parkinson disease (PD) is either the internal globus pallidus or the subthalamic nucleus (STN); the target for treatment of essential tremor (ET) is the thalamic subnucleus ventralis intermedius (Vim). Some patients with PD have coexistent ET, and the identification of a single surgical target to treat both parkinsonian motor symptom...
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ژورنال
عنوان ژورنال: Parkinsonism & Related Disorders
سال: 2021
ISSN: 1353-8020
DOI: 10.1016/j.parkreldis.2020.12.001