Densitometric High Performance Thin-Layer Chromatography Identification and Quantitative Analysis of Psychotropic Drugs

Simultaneous thin-layer chromatography-densitometric analysis of sibutramine and citalopram.

Due the presence of sibutramine and citalopram in a number of drugs, neurotransmitter reuptake inhibitors. Sibutramine reduces the reuptake of serotonin, norepinephrine, and dopamine; citalopram is an antidepressant drug of the selective serotonin reuptake inhibitor. The thin-layer chromatography-densitometric behavior of some centrally acting serotonin reuptake inhibitors has been studied. The...

Quantitative Estimation of Efavirenz by High Performance Thin Layer Chromatography

A simple, accurate, and precise HPTLC method has been developed and validated for the estimation of efavirenz from bulk drug and capsule formulations. The separation was achieved on TLC plates using an appropriate solvent system. The spots so developed were densometrically scanned at 247 nm. The linearity of the method was found to be within the concentration range of 1-40 μg/ml. The validation...

Christhin: Quantitative Analysis of Thin Layer Chromatography

A copy of the license is included in the section entitled " GNU Free Documentation License ". Acknowledgments We thank CONICET, the Secretaría de Ciencia, Tecnologia e Innovación, Gobierno de la Provincia de Chubut and the Consejo Interuniversitario Nacional (CIN) for supporting this development. We also thank Dr. Héctor " Tito " Fernández and Dr. Nazareno Aguirre for their help.

Lipid Analysis by Quantitative Thin-layer Chromatography.

Quantitative Analysis of Valsartan and Hydrochlorothiazide in Tablets by High Performance Thin-layer Chromatography

A new, simple, accurate, and precise high-performance thin-layer chromatographic (HPTLC) method has been established for simultaneous analysis of valsartan and hydrochlorothiazide in tablet formulations. Standard and sample solutions of valsartan and hydrochlorothiazide were applied to precoated silica gel G 60 F254 HPTLC plates and the plates were developed with chloroform–ethyl acetate–acetic...