Denitrogenative Suzuki and carbonylative Suzuki coupling reactions of benzotriazoles with boronic acids
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منابع مشابه
Denitrogenative Suzuki and carbonylative Suzuki coupling reactions of benzotriazoles with boronic acids† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc00367f Click here for additional data file.
متن کامل
Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides.
A protocol for the Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides that minimizes protodeboronation is described. A combination of catalytic amounts of Pd(OAc)(2) and SPhos in conjunction with CsF in isopropanol effectively affords a variety of coupled products. Surprisingly, a dramatic temperature dependence in product selectivity was observed.
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Among cross-coupling reactions, the Suzuki-Miyaura transformation stands out because of its practical advantages, including the commercial availability and low toxicity of the required reagents, mild reaction conditions, and functional group compatibility. Nevertheless, few conditions can be used to cross-couple alkyl boronic acids or esters with aryl halides, especially 2-pyridyl halides. Here...
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2017
ISSN: 2041-6520,2041-6539
DOI: 10.1039/c7sc00367f