Deleterious Passengers in Adapting Populations
نویسندگان
چکیده
منابع مشابه
Deleterious passengers in adapting populations.
Most new mutations are deleterious and are eventually eliminated by natural selection. But in an adapting population, the rapid amplification of beneficial mutations can hinder the removal of deleterious variants in nearby regions of the genome, altering the patterns of sequence evolution. Here, we analyze the interactions between beneficial "driver" mutations and linked deleterious "passengers...
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ژورنال
عنوان ژورنال: Genetics
سال: 2014
ISSN: 1943-2631
DOI: 10.1534/genetics.114.170233