Delayed and acute hemolytic transfusion reactions resulting from red cell antibodies and red cell-reactive HLA antibodies
نویسندگان
چکیده
منابع مشابه
Delayed hemolytic transfusion reactions.
Delayed hemolytic transfusion reactions continue to occur in spite of the use of all of the currently available techniques of antibody detection. Both low titers of the antibodies and dosage effects appear to contribute to the failure of detection. A rapid anamnestic response can occur with transfusion of the appropriate antigen. The clinical as well as the laboratory presentation of delayed he...
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TRALI is considered a serious hazard among immune complications of blood transfusion and its occurrence is admitted to be globally underestimated. Each type of blood product is likely to cause TRALI. We report here on two consecutive observations of TRALI caused by red blood cell concentrates, in which anti-HLA class I and class II antibodies resulting from post-gravitational allo-immunization ...
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Background and Aims: A subgroup of group O individuals called ‘dangerous universal donors’ have immune (IgG) anti A and anti B antibodies which are active at 37˚C and capable of reacting with the red cells and causing lysis. The aim of this study was to find the prevalence of dangerous O group among the voluntary donor population and to assess the relation between the degree of haemolysis and t...
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Background: Anti-HLA-antibodies are known to affect the allograft survival in transplant recipient patients. Objective: The aim of this study was to evaluate the association between anti-HLA antibodies and kidney allograft outcomes, particularly in recipients with concur-rent donor bone marrow cell infusion (DBMI). Methods: Between June 2006 and May 2007, forty living unrelated donor kidney tra...
متن کاملRed Blood Cell Transfusion Practices
Red blood cell (RBC) transfusion therapy is used in the clinical setting for a variety of indications, including patient resuscitation, augmentation of oxygen delivery, and to reverse or alleviate the symptoms of anemia [1–5]. Despite calls for a more conservative approach to blood transfusion as early as the late 1950s [6,7], the trend toward more cautious transfusion practices did not begin u...
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ژورنال
عنوان ژورنال: Transfusion
سال: 2005
ISSN: 0041-1132,1537-2995
DOI: 10.1111/j.1537-2995.2005.00607.x