Definition, classification and mechanism of action of endocrine disrupting chemicals
نویسندگان
چکیده
منابع مشابه
Definition, classification and mechanism of action of endocrine disrupting chemicals.
Address for correspondence: Prof. Dr. Wolfgang Wuttke, Department of Endocrinology, University Medical Center Goettingen, Georg-AugustUniversity, Robert-Koch-Strasse 40, D-37099 Goettingen/ Germany, Tel.: +49-551-396714, Fax: +49-551-396518, E-mail: [email protected] Received 10-11-09, Revised 12-12-09, Accepted 2 -12-09
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The incidence and/or prevalence of health problems associated with endocrine-disruption have increased. Many chemicals have endocrine-disrupting properties, including bisphenol A, some organochlorines, polybrominated flame retardants, perfluorinated substances, alkylphenols, phthalates, pesticides, polycyclic aromatic hydrocarbons, alkylphenols, solvents, and some household products including s...
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Synthetic endocrine disrupting chemicals (EDCs), omnipresent in food, household, and personal care products, have been implicated in adverse trends in human reproduction, including infertility and increasing demand for assisted reproduction. Here, we study the action of 96 ubiquitous EDCs on human sperm. We show that structurally diverse EDCs activate the sperm-specific CatSper channel and, the...
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ژورنال
عنوان ژورنال: HORMONES
سال: 2010
ISSN: 1109-3099
DOI: 10.14310/horm.2002.1252